Northwestern University Feinberg School of Medicine

The Ken & Ruth Davee Department of Neurology

Jay A Gottfried, MD, PhD

Jay A Gottfried, MD, PhD

Adjunct Professor of Neurology (Behavioral Neurology)

Focus of Work

Bio

My research focuses on understanding how the human brain transforms odor inputs into olfactory percepts (such as the smell of mint, banana, or wet dog), and how learning, memory, and experience modulate odor perception at the neural and behavioral levels. To address these questions we use a combination of techniques including high-resolution olfactory functional magnetic resonance imaging (fMRI), multivariate statistical analyses, psychophysical paradigms, and physiological recordings. Given th...[Read full text]My research focuses on understanding how the human brain transforms odor inputs into olfactory percepts (such as the smell of mint, banana, or wet dog), and how learning, memory, and experience modulate odor perception at the neural and behavioral levels. To address these questions we use a combination of techniques including high-resolution olfactory functional magnetic resonance imaging (fMRI), multivariate statistical analyses, psychophysical paradigms, and physiological recordings. Given that patients with Alzheimer’s disease (AD) exhibit profound impairments in the sense of smell, I am also investigating whether olfactory fMRI techniques can be effectively used as a non-invasive diagnostic biomarker to identify asymptomatic individuals at risk for developing AD.

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Education and Certification

  • MD, PhD: New York U (1997)
  • Residency: Hospital of the University of Pennsylvania (2001)
  • Board Certification: Neurology